C R Biol. 2007 Jun-Jul;330(6-7):557-60. Epub 2007 May 9.

Repair of spinal cord injury by transplantation of olfactory ensheathing cells.

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Spinal Repair Unit, Institute of Neurology, UCL, Queen Square, London WC1N 3BG, UK. g.raisman@ion.ucl.ac.uk

Abstract

Repair of spinal cord injury requires that severed axons are able to regenerate. Regrowth of axons is impeded by the loss of astrocytic pathways caused at the time of injury. Ensheathing glial cells cultured from the adult olfactory system can be transplanted into lesions and mediate both regeneration of axons and recovery of function.

PMID:: 17631453; [PubMed - indexed for MEDLINE]

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Review Interaction of olfactory ensheathing cells with astrocytes may be the key to repair of tract injuries in the spinal cord: the 'pathway hypothesis'. [J Neurocytol. 2005]
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