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Neurol Neurochir Pol. 2007 May-Jun;41(3):259-66.

[Multiple sclerosis and other autoimmune diseases].

[Article in Polish]

Author information

  • 1Katedra i Klinika Neurologii, Akademia Medyczna im. prof. Feliksa Skubiszewskiego w Lublinie, Lublin. ewbel@poczta.onet.pl

Abstract

Autoimmune diseases are caused by a defect of the human immune system characterised by an inability to recognize their own antigens and by a pathological response against these antigens. Although the aetiology of these diseases is unknown, there is a number of cellular and molecular mechanisms which can underlie these reactions. Complex interactions between genetic, infectious and/or environmental factors probably contribute to the presence of these diseases. Autoimmune diseases affect 3-8% of the general population; women account for 78-85% of all patients with autoimmune diseases. Although most of those diseases are systemic, some of them primarily affect a single organ or structure. Rarely, a few autoimmune diseases coexist in one person, which can suggest similar pathogenetic mechanisms. In this article we present a review of the literature on coexistence of multiple sclerosis and other autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, chronic active hepatitis, type 1 diabetes mellitus, uveitis, pemphigus, psoriasis, Crohn's disease, inflammatory bowel disease, anaemia and autoimmune thyroiditis.

PMID:
17629820
[PubMed - indexed for MEDLINE]
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