Your browser version may not work well with NCBI's Web applications. More information here...
1: Int J Artif Organs. 2007 Jun;30(6):513-9.Links

Feasibility of mesothelial transplantation during experimental peritoneal dialysis and peritonitis.

Hekking LH, van den Born J.

Department of Cellular Architecture and Dynamics, University of Utrecht, Utrecht, The Netherlands.

The mesothelial cell layer lining the peritoneum orchestrates peritoneal homeostasis. Continuous exposure to peritoneal dialysis fluids and episodes of peritonitis may damage the monolayer irreversibly, eventually leading to adhesion formation and fibrosis/sclerosis of the peritoneum. Autologous mesothelial cell transplantation is thought to be one of the options to reduce dysfunction of the peritoneal membrane. In this article we will review the mesothelial cell transplantation experiments performed in the field of peritoneal dialysis and peritonitis. In addition we will focus on the trouble shooting using cultured autologous mesothelial cells for transplantation.

PMID: 17628852 [PubMed - indexed for MEDLINE]

Related Articles