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Service de dermatologie, hôpital Edouard-Herriot, pavillon R, 5, place d'Arsonval, 69437 Lyon cedex 03, France. michel.faure@chu-lyon.fr
Acne is an androgen-dependant inflammatory folliculitis with non-inflammatory lesions (open and closed comedos) and inflammatory papules, pustules and sometimes nodules. Topical retinoïds, benzoyl peroxyde, antibiotics with anti-inflammatory properties, antiandrogens in female acne (antiandrogens and antiandrogenic oral contraceptives), and isotretinoin are the major drugs used in the management of the affection. Acne has to be treated according to the type of acne, severity, age and sex. Acne may also be the major sign of ovarian (PCOS) or adrenal hyperandrogenism in either female teenagers or both sexes, respectively.
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