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Eur Urol. 2008 Mar;53(3):540-4. Epub 2007 Jul 2.

Erectile function in prostate cancer-free patients who underwent prostate saturation biopsy.

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  • 1Department of Urology, Marmara University School of Medicine, Istanbul, Turkey. cakbal@gmail.com

Abstract

OBJECTIVE:

To evaluate the erectile function following transrectal ultrasound-guided saturation biopsies of the prostate.

MATERIALS AND METHODS:

Of the 150 patients included in the study, those with persistently elevated prostate-specific antigen (PSA) level underwent saturation biopsy. A median of 22-core (minimum: 20; maximum: 30) prostate saturation biopsies was taken. Patients were evaluated for erectile function prebiopsy with the 5-item version of the International Index of Erectile Function (IIEF-5) and the IIEF-Erectile Function (IIEF-EF) domain scoring. Concomitant systemic diseases and medications that would interfere with erectile function were recorded. Eighty-eight patients reported to be prostate cancer-free underwent further evaluation with the IIEF-5 questionnaire at 1 and 6 mo postbiopsy. Severity of erectile dysfunction (ED) was classified into four categories.

RESULTS:

The patients' ages, serum PSA levels, prostate volumes, and number of cores showed no significant correlation with changes in ED scores after the prostate saturation biopsies. According to the IIEF-5, for patients who were previously potent and found to be free of prostate cancer, the ED rates were 11.6% at the first month, and no ED was reported at the sixth month of evaluation. IIEF-5 and IIEF-EF domain scores displayed a statistically significant difference between baseline and first-month scores, but not between baseline and sixth-month scores, which returned to baseline values.

CONCLUSIONS:

Although saturation biopsy of the prostate is a safe procedure on the basis of erectile function, the minimal risk of temporary postbiopsy ED should be discussed with previously potent patients.

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PMID:
17619078
[PubMed - indexed for MEDLINE]
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