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J Cardiothorac Surg. 2007 Jun 28;2:29.

Pleural inflammatory myofibroblastoma: a locally aggressive intra-thoracic tumour.

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  • 1Department of Cardiothoracic Surgery, Cardiothoracic Centre, Thomas Drive, Liverpool, L14 3PE, UK.


A 41-year old non-smoking woman presented with persistent pleural effusion. Pleural fluid was hemorrhagic and fluid cytology was negative for malignant cells. A working diagnosis of chronic haemothorax was made and standard right thoracotomy was performed to identify the source of bleeding. A 10 x 10 cms poorly circumscribed mass containing blood clots, altered blood, fibrous tissue, and gelatinous debris was found and demonstrated features of inflammatory myofibroblastoma on immunohistochemistry. Thirteen months later, the patient developed a local recurrence, which was treated surgically. Semi-solid physical appearance of this tumour has not been reported previously. This case report further adds to the diagnostic dilemma related with this tumour.

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