Observed PCER and observed FDR of the alpha-spending algorithm as a function of power of the ordinary t-test for different correlations ρ = 0.3, 0.5, 0.7 and different group sizes n = 4, 6,10 for k = 700 . The number of genes in each simulation was 700 and the nominal alpha levels of 0.05 was used for identifying differential genes. A thin dashed black line, a solid blue line, and a thick red line refer to a correlation ρ of 0.3, 0.5, and 0.7, respectively. The group sizes of 4, 6, and 10 are represented by circles, squares, and triangles, respectively. In each simulation parameter setting (ρ , n) the observed PCER was estimated from 100 simulated data sets