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Nurs Sci Q. 2007 Jul;20(3):254-64.

The Theory of Genetic Vulnerability: a Roy model exemplar.

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  • 1University of Pittsburgh, Pittsburgh, Pennsylvania, USA.


The purpose of this study was to explore the experience of adult genetic testing. Grounded theory was used to plan, guide, and analyze in-depth interviews with 29 participants. The theory of genetic vulnerability was developed and is composed of five concepts: (a) experiencing the family disease, (b) testing for a mutation, (c) fore-grounding inherited disease risk, (d) responding to knowledge of genetic vulnerability, and (e) altering or avoiding the family experience of inherited disease. Roy's model of adaptation is discussed as a valuable lens through which to test and adapt this theory.

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