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Chem Commun (Camb). 2007 Jul 14;(26):2714-6. Epub 2007 Apr 19.

Reversible folding-unfolding, aggregation protection, and multi-year stabilization, in high concentration protein solutions, using ionic liquids.

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  • 1Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA.

Abstract

We report the reversible thermal unfolding/refolding, and long period stabilization against aggregation and hydrolysis, of >200 mg ml(-1) solutions of lysozyme in ionic liquid-rich, ice-avoiding, solvents.

PMID:
17594030
[PubMed - indexed for MEDLINE]
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