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Nat Biotechnol. 2007 Jul;25(7):763-9. Epub 2007 Jun 24.

Complete genome sequence of the fish pathogen Flavobacterium psychrophilum.

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  • 1INRA, Unité Virologie et Immunologie Moléculaires UR892, F-78350 Jouy-en-Josas, France. eric.duchaud@jouy.inra.fr

Abstract

We report here the complete genome sequence of the virulent strain JIP02/86 (ATCC 49511) of Flavobacterium psychrophilum, a widely distributed pathogen of wild and cultured salmonid fish. The genome consists of a 2,861,988-base pair (bp) circular chromosome with 2,432 predicted protein-coding genes. Among these predicted proteins, stress response mediators, gliding motility proteins, adhesins and many putative secreted proteases are probably involved in colonization, invasion and destruction of the host tissues. The genome sequence provides the basis for explaining the relationships of the pathogen to the host and opens new perspectives for the development of more efficient disease control strategies. It also allows for a better understanding of the physiology and evolution of a significant representative of the family Flavobacteriaceae, whose members are associated with an interesting diversity of lifestyles and habitats.

PMID:
17592475
[PubMed - indexed for MEDLINE]
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