Characterization of a catalase-negative methicillin-resistant Staphylococcus aureus strain

J Clin Microbiol. 2007 Aug;45(8):2684-5. doi: 10.1128/JCM.02457-06. Epub 2007 Jun 20.

Abstract

We describe an unusual clinical strain of catalase-negative methicillin-resistant Staphylococcus aureus sensu stricto. Sequence analysis of its catalase gene showed 99.60% identities to the catalase genes of the reference strains. A 5-base deletion, however, led to a shift of the nucleotide reading frame and a loss of the enzymatic activity.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Catalase / genetics*
  • Catalase / metabolism*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Humans
  • Male
  • Methicillin Resistance*
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / enzymology*
  • Staphylococcus aureus / isolation & purification

Substances

  • DNA, Bacterial
  • Catalase

Associated data

  • GENBANK/EF140590