Format

Send to:

Choose Destination
See comment in PubMed Commons below
Clin Pharmacol Ther. 2007 Jul;82(1):17-20.

Diagnosing model diagnostics.

Author information

  • 1Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden. mats.karlsson@farmbio.uu.se

Abstract

Conclusions from clinical trial results that are derived from model-based analyses rely on the model adequately describing the underlying system. The traditionally used diagnostics intended to provide information about model adequacy have seldom discussed shortcomings. Without an understanding of the properties of these diagnostics, development and use of new diagnostics, and additional information pertaining to the diagnostics, there is risk that adequate models will be rejected and inadequate models accepted. Thus, a diagnosis of available diagnostics is desirable.

PMID:
17571070
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Write to the Help Desk