Pediatr Radiol. 2007 Jul;37(7):615-22. Epub 2007 May 22.

PET-CT in pediatric Langerhans cell histiocytosis.

Kaste SC, Rodriguez-Galindo C, McCarville ME, Shulkin BL.

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Division of Diagnostic Imaging, Department of Radiological Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105-2794, USA. sue.kaste@stjude.org

Abstract

Our objective was to assess the utility of PET-CT in five pediatric patients with Langerhans cell histiocytosis (LCH) who underwent PET-CT imaging for clinical staging and determination of lesion activity at various stages of treatment and follow-up. PET-CT combines the anatomic detail of CT and the physiologic activity of (18)F-FDG imaging. We conclude that PET-CT information is clinically useful to evaluate disease activity and response to therapy and provides information that cannot be obtained from technetium 99m methylene diphosphonate bone scans or radiographs.

PMID:: 17564738; [PubMed - indexed for MEDLINE]

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