C R Acad Sci III. 1991;313(8):345-51.

Expression of a gene encoding a novel potential IGF binding protein in human tissues.

Source

Laboratoire d'Oncologie virale et moléculaire, Institut Curie, Centre Universitaire, Orsay.

Abstract

We have shown in a previous study that the expression of an as yet unidentified, embryonic gene (nov) encoding a potential IGF binding protein was upregulated in all of eight virally-induced avian nephroblastomas tested. We now report that homologous sequences are conserved in human DNA and are expressed in normal human bone marrow, thymic cells and in one nephroblastoma.

PMID:: 1756408; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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Medical

Wilm's Tumor - Genetic Alliance

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Related citations in PubMed

Structural analysis of the human nov proto-oncogene and expression in Wilms tumor. [Oncogene. 1994]
Structural analysis of the human nov proto-oncogene and expression in Wilms tumor.
Martinerie C, Huff V, Joubert I, Badzioch M, Saunders G, Strong L, Perbal B. Oncogene. 1994 Sep; 9(9):2729-32.
Regulation of nov by WT1: a potential role for nov in nephrogenesis. [Oncogene. 1996]
Regulation of nov by WT1: a potential role for nov in nephrogenesis.
Martinerie C, Chevalier G, Rauscher FJ 3rd, Perbal B. Oncogene. 1996 Apr 4; 12(7):1479-92.
Eel WT1 sequence and expression in spontaneous nephroblastomas in Japanese eel. [Gene. 2000]
Eel WT1 sequence and expression in spontaneous nephroblastomas in Japanese eel.
Nakatsuru Y, Minami K, Yoshikawa A, Zhu J, Oda H, Masahito P, Okamoto N, Nakamura Y, Ishikawa T. Gene. 2000 Mar 21; 245(2):245-51.
SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours. [Br J Cancer. 2006]
SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours.
Singh KP, Roy D. Br J Cancer. 2006 May 22; 94(10):1524-32.
Review Contribution of MAV-1-induced nephroblastoma to the study of genes involved in human Wilms' tumor development. [Crit Rev Oncog. 1994]
Review Contribution of MAV-1-induced nephroblastoma to the study of genes involved in human Wilms' tumor development.
Perbal B. Crit Rev Oncog. 1994; 5(6):589-613.

See reviews... See all...

Cited by 2 PubMed Central articles

The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling. [Proc Natl Acad Sci U S A. 1999]
The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling.
Perbal B, Martinerie C, Sainson R, Werner M, He B, Roizman B. Proc Natl Acad Sci U S A. 1999 Feb 2; 96(3):869-74.
Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas. [Mol Cell Biol. 1992]
Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.
Joliot V, Martinerie C, Dambrine G, Plassiart G, Brisac M, Crochet J, Perbal B. Mol Cell Biol. 1992 Jan; 12(1):10-21.

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Related Citations
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Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
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Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
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Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Cited in PMC
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