Methods. 2007 Aug;42(4):388-93.

The inner gel component of Aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells.

Habeeb F, Stables G, Bradbury F, Nong S, Cameron P, Plevin R, Ferro VA.

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Faculty of Allied Health, Medical Laboratory Sciences, Kuwait University, P.O. Box 31470, Sulaibikhat 90805, Kuwait. fmhabeeb@hsc.edu.kw

Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-alpha and IL-1 beta, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

PMID:: 17560326; [PubMed - indexed for MEDLINE]

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