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Acta Psychiatr Scand. 2007 Jul;116(1):62-70.

Prevalence and correlates of comorbidity 8 years after a first psychotic episode.

Author information

  • 1ORYGEN Research Centre & Department of Psychiatry, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.

Abstract

OBJECTIVE:

While rates and correlates of comorbidity have been investigated in the early course of psychosis, little is known about comorbidity in the medium-to-longer term or its relationship with outcome.

METHOD:

A total of 182 first-episode psychosis (FEP) patients who met DSM-IV criteria for a current psychotic disorder 8 years after index presentation were grouped according to concurrent comorbidity [no concurrent axis I disorder; concurrent substance use disorder (SUD); other concurrent axis I disorder; concurrent SUD and other axis I disorder]. Outcomes were compared between groups controlling for relevant covariates.

RESULTS:

As much as 39% met criteria for one or more concurrent axis 1 diagnoses. Comorbidity was associated with greater severity of general psychopathology, but not with measures of functioning, treatment or negative symptoms.

CONCLUSION:

Specific combinations of comorbid disorders may influence patterns of psychotic symptomatology. Routine examination of axis I disorders is warranted in the ongoing management of psychosis.

PMID:
17559602
[PubMed - indexed for MEDLINE]
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