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    Neuron. 2007 Jun 7;54(5):673-5.

    Hierarchical control of sensory neuron development by neurotrophic factors.

    Source

    Department of Neuroscience, Karolinska Institute, 17177 Stockholm, Sweden. carlos.ibanez@ki.se

    Abstract

    We are still far from reaching a complete understanding of the molecular mechanisms that control neuronal diversification during nervous system development. In this issue of Neuron, Luo et al. bring that goal a step closer by revealing how a hierarchical interaction between two neurotrophic factor systems drives the differentiation, maturation, and extension of peripheral projections in a subclass of sensory neurons that mediate pain perception.

    PMID:
    17553418
    [PubMed - indexed for MEDLINE]

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