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Opt Lett. 2007 Jun 1;32(11):1572-4.

Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy.

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  • 1G.R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. minwah@mit.edu

Abstract

We describe a heterodyne Mach-Zehnder interferometric microscope capable of quantitative phase imaging of biological samples with subnanometer sensitivity and frame rates up to 10 kHz. We use the microscope to image cultured neurons and measure nanometer-scale voltage-dependent motions in cells expressing the membrane motor protein prestin.

PMID:
17546192
[PubMed - indexed for MEDLINE]
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