AIDS. 2007 Jun 19;21(10):1377-9.

Effect of GB virus C co-infection on response to generic HAART in African patients with HIV-1 clade C infection.

Mosam A, Sathar MA, Dawood H, Cassol E, Esterhuizen TM, Coovadia HM.

Source

Medical Bioethics Unit, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

Abstract

In 38 African AIDS patients initiating generic HAART, GB virus C (GBV-C) RNA-positive patients retained GBV-C viraemia during 52 weeks of HAART, had a faster decline in HIV viral load (P = 0.03), fewer opportunistic infections (14.3 versus 50%, P = 0.18), and suffered no serious adverse events (none versus 61%, P = 0.008) compared with patients without GBV-C. GBV-C co-infection may be associated with a beneficial effect on African AIDS patients treated with generic HAART.