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VIPER: an advanced software package to support high-throughput LC-MS peptide identification.
Pacific Northwest National Laboratory, Richland, WA 99354, USA.
SUMMARY: The accurate mass and time (AMT) tag approach is used for analysis of large scale experiments by combining information generated over multiple datasets and instrument types. The VIPER software package is one of the key components of the data processing pipeline and implements automated algorithms to discover LC-MS features, align and match these LC-MS features to a database of peptides previously identified in LC-MS/MS analyses, and identify and quantify pairs of isotopically labeled peptides. AVAILABILITY: VIPER may be downloaded free of charge at http://ncrr.pnl.gov/software/
PMID: 17545182 [PubMed - indexed for MEDLINE]
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Cited by 12 PubMed Central articles
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Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data.
Jaitly N, Mayampurath A, Littlefield K, Adkins JN, Anderson GA, Smith RD.
BMC Bioinformatics. 2009 Mar 17; 10:87. Epub 2009 Mar 17.
[BMC Bioinformatics. 2009]
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Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation.
Ansong C, Yoon H, Porwollik S, Mottaz-Brewer H, Petritis BO, Jaitly N, Adkins JN, McClelland M, Heffron F, Smith RD.
PLoS One. 2009; 4(3):e4809. Epub 2009 Mar 11.
[PLoS One. 2009]
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Optimization of proteomic sample preparation procedures for comprehensive protein characterization of pathogenic systems.
Mottaz-Brewer HM, Norbeck AD, Adkins JN, Manes NP, Ansong C, Shi L, Rikihisa Y, Kikuchi T, Wong SW, Estep RD, et al.
J Biomol Tech. 2008 Dec; 19(5):285-95.
[J Biomol Tech. 2008]
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