Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Complement Ther Med. 2007 Jun;15(2):128-38. Epub 2007 Mar 28.

The in vitro evidence for an effect of high homeopathic potencies--a systematic review of the literature.

Author information

  • 1Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, D-10098 Berlin, Germany. claudia.witt@charite.de

Abstract

OBJECTIVE:

Systematic assessment of the in vitro research on high potency effects.

METHOD:

Publications of experiments were collected through databases, experts, previous reviews, citation tracking. Inclusion criteria: stepwise agitated dilutions <10(-23); cells or molecules from human or animal. Experiments were assessed with the modified SAPEH score.

RESULTS:

From 75 publications, 67 experiments (1/3 of them replications) were evaluated. Nearly 3/4 of them found a high potency effect, and 2/3 of those 18 that scored 6 points or more and controlled contamination. Nearly 3/4 of all replications were positive. Design and experimental models of the reviewed experiments were inhomogenous, most were performed on basophiles.

CONCLUSIONS:

Even experiments with a high methodological standard could demonstrate an effect of high potencies. No positive result was stable enough to be reproduced by all investigators. A general adoption of succussed controls, randomization and blinding would strengthen the evidence of future experiments.

Comment in

PMID:
17544864
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk