Bioinformatics. 2007 Aug 1;23(15):2013-4. Epub 2007 May 31.

Tree Gibbs Sampler: identifying conserved motifs without aligning orthologous sequences.

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Division of Biostatistics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.

Abstract

SUMMARY: Tree Gibbs Sampler is a software for identifying motifs by simultaneously using the motif overrepresentation property and the motif evolutionary conservation property. It identifies motifs without depending on pre-aligned orthologous sequences, which makes it useful for the extraction of regulatory elements in multiple genomes of both closely related and distant species. AVAILABILITY: The Tree Gibbs Sampler software is freely downloadable at https://compbio.iupui.edu/xiaomanli/LiSoftware/retrieve.php?ID=tgs

PMID:: 17540681; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

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