Send to:

Choose Destination
See comment in PubMed Commons below
Chem Soc Rev. 2007 Jun;36(6):856-68. Epub 2007 Feb 15.

Locking self-assembly: strategies and outcomes.

Author information

  • 1Department of Chemistry, University of Sheffield, Sheffield, UK.

Erratum in

  • Chem Soc Rev. 2007 Jun;36(6):1018.


In the last ten to fifteen years, self-assembly has been increasingly employed to construct discrete supramolecular structures. In most cases, due to the thermodynamic factors that drive the self-assembly process, the final architectures produced by this approach are not kinetically robust. Thus, when robust structures are required a "self-assembly followed by covalent modification" strategy has been commonly applied. However, over the last decade an alternative strategy has emerged. Several methods for "locking" self-assembly, and thus yielding kinetically inert products have been developed. This review outlines the main strategies that have been employed towards such aims and describes some of the properties that result from the enhanced stability of product architectures.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry
    Loading ...
    Write to the Help Desk