Abstract
Pneumatosis intestinalis and gas within the portal venous system are findings predictive of bowel ischemia. The etiologies of these alarming radiographic signs are diverse and not all causes require emergent surgical intervention. The combination of pneumatosis intestinalis, portal venous gas, and acidosis typically portends bowel ischemia and inevitable necrosis. This case report is the first description of benign pneumatosis and portal venous gas secondary to irinotecan and cisplatin.
MeSH terms
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Aged
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Antineoplastic Agents / adverse effects*
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Antineoplastic Agents / therapeutic use
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Camptothecin / adverse effects
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Camptothecin / analogs & derivatives*
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Camptothecin / therapeutic use
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Cisplatin / adverse effects*
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Cisplatin / therapeutic use
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Colon / blood supply
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Diagnosis, Differential
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Embolism, Air / chemically induced*
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Embolism, Air / diagnostic imaging
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Esophageal Neoplasms / drug therapy
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Follow-Up Studies
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Humans
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Intestine, Small / blood supply
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Irinotecan
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Ischemia / diagnosis*
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Ischemia / surgery
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Laparotomy
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Male
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Pneumatosis Cystoides Intestinalis / chemically induced*
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Pneumatosis Cystoides Intestinalis / diagnostic imaging
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Portal Vein*
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Prodrugs
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Tomography, X-Ray Computed
Substances
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Antineoplastic Agents
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Prodrugs
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Irinotecan
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Cisplatin
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Camptothecin