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Eur J Clin Nutr. 2008 May;62(5):682-5. Epub 2007 May 16.

Effects of a short-term intervention with a paleolithic diet in healthy volunteers.

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  • 1Department of Neurobiology, Center for Family and Community Medicine, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.

Abstract

OBJECTIVES:

Prevention of cardiovascular diseases by paleolithic or hunter-gatherer diets has been discussed during recent years.

METHODS:

Our aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study. Complete dietary assessment was available for six subjects.

RESULTS:

Mean weight decreased by 2.3 kg (P<0.001), body mass index by 0.8 (P<0.001), waist circumference by 0.5 cm (P=0.001), systolic blood pressure by 3 mm Hg (P=0.03) and plasminogen activator inhibitor-1 by 72% (P=0.020). Regarding nutrient intake, intake of energy decreased by 36%, and other effects were also observed, both favourable (fat composition, antioxidants, potassium-sodium rate) and unfavourable (calcium).

CONCLUSION:

This short-term intervention showed some favourable effects by the diet, but further studies, including control group, are needed.

PMID:
17522610
[PubMed - indexed for MEDLINE]
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