Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, MD 20850, USA. liw@umbi.umd.edu
We report the development of a new reagent, called CILAT (Cleavable Isobaric Labeled Affinity Tag), for quantitative proteomics, which represents an improvement over current ICAT (Isotope-Coded Affinity Tag) and iTRAQ (Isobaric Tags for Relative and Absolute Quantitation) methods.