Department of Pediatrics, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway. brwylle@online.no
We describe the effect of propranolol in an adolescent with chronic fatigue syndrome and orthostatic intolerance. Our observations suggest that the head-up tilt-test and beta-blocker treatment might be considered in patients with chronic fatigue syndrome and that enhanced sympathetic nervous activity might be part of the underlying pathophysiology.