Clin EEG Neurosci. 2007 Apr;38(2):105-15.

Transcranial and deep brain stimulation approaches as treatment for depression.

Rau A, Grossheinrich N, Palm U, Pogarell O, Padberg F.

Source

Dept. of Psychiatry and Psychotherapy, Ludwig-Maximilians University Munich, Munich, Germany.

Abstract

Given that a considerable portion of depressed patients does not respond to or remit during pharmacotherapy, there is increasing interest in non-pharmacological strategies to treat depressive disorders. Several brain stimulation approaches are currently being investigated as novel therapeutic interventions beside electroconvulsive therapy (ECT), a prototypic method in this field with proven effectiveness. These neurostimulation methods include repetitive transcranial magnetic stimulation (rTMS), magnetic seizure therapy (MST), vagus nerve stimulation (VNS), deep brain stimulation (DBS) and transcranial direct current stimulation (tDCS). It is via different neuroanatomically defined "windows" that the various approaches access the neuronal networks showing an altered function in depression. Also, the methods vary regarding their degree of invasiveness. One or the other method may finally achieve antidepressant effectiveness with minimized side effects and constitute a new effective treatment for major depression.

PMID:: 17515176; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Education

New England Research Institutes Inc.

Medical

Depression - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Review [New techniques of electrical and magnetic stimulation in treatment of depression--comparison with electroconvulsive treatment and pharmacotherapy]. [Psychiatr Pol. 2010]
Review [New techniques of electrical and magnetic stimulation in treatment of depression--comparison with electroconvulsive treatment and pharmacotherapy].
Zyss T. Psychiatr Pol. 2010 Nov-Dec; 44(6):853-69.
Review [Transcranial direct current stimulation and related techniques in treatment of psychiatric disorders]. [Psychiatr Pol. 2010]
Review [Transcranial direct current stimulation and related techniques in treatment of psychiatric disorders].
Zyss T. Psychiatr Pol. 2010 Jul-Aug; 44(4):505-18.
Review [Electroconvulsive treatment and new techniques of electrical and magnetic stimulation in treatment of depression--question of placebo and warranting of blind conditions, as well as other methodological problems]. [Psychiatr Pol. 2011]
Review [Electroconvulsive treatment and new techniques of electrical and magnetic stimulation in treatment of depression--question of placebo and warranting of blind conditions, as well as other methodological problems].
Zyss T. Psychiatr Pol. 2011 Jan-Feb; 45(1):97-116.
Review Treatment resistant depression--advances in somatic therapies. [Ann Clin Psychiatry. 2007]
Review Treatment resistant depression--advances in somatic therapies.
Kennedy SH, Giacobbe P. Ann Clin Psychiatry. 2007 Oct-Dec; 19(4):279-87.
Brain stimulation techniques for the treatment of depression and other psychiatric disorders. [Australas Psychiatry. 2008]
Brain stimulation techniques for the treatment of depression and other psychiatric disorders.
Fitzgerald P. Australas Psychiatry. 2008 Jun; 16(3):183-90.

See reviews... See all...

Cited by 2 PubMed Central articles

Dual-hemisphere tDCS facilitates greater improvements for healthy subjects' non-dominant hand compared to uni-hemisphere stimulation. [BMC Neurosci. 2008]
Dual-hemisphere tDCS facilitates greater improvements for healthy subjects' non-dominant hand compared to uni-hemisphere stimulation.
Vines BW, Cerruti C, Schlaug G. BMC Neurosci. 2008 Oct 28; 9:103. Epub 2008 Oct 28.
Whole-body cryotherapy as adjunct treatment of depressive and anxiety disorders. [Arch Immunol Ther Exp (Warsz)....]
Whole-body cryotherapy as adjunct treatment of depressive and anxiety disorders.
Rymaszewska J, Ramsey D, Chładzińska-Kiejna S. Arch Immunol Ther Exp (Warsz). 2008 Jan-Feb; 56(1):63-8. Epub 2008 Feb 5.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Transcranial and deep brain stimulation approaches as treatment for depression.
Transcranial and deep brain stimulation approaches as treatment for depression.
Clin EEG Neurosci. 2007 Apr ;38(2):105-15.

PubMed
Cardiac glycosides in cancer research and cancer therapy.
Cardiac glycosides in cancer research and cancer therapy.
Acta Pol Pharm. 2006 Mar-Apr ;63(2):109-15.

PubMed
Acquired pigmentation simulating Peutz-Jeghers syndrome: initial manifestation o...
Acquired pigmentation simulating Peutz-Jeghers syndrome: initial manifestation of diffuse uveal melanocytic proliferation.
Br J Ophthalmol. 1991 Nov ;75(11):693-5.

PubMed
Serum androgens and prostate cancer among 643 cases and 643 controls in the Euro...
Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition.
Int J Cancer. 2007 Sep 15 ;121(6):1331-8.

PubMed
Effects of repeated doses of caffeine on performance and alertness: new data and...
Effects of repeated doses of caffeine on performance and alertness: new data and secondary analyses.
Hum Psychopharmacol. 2007 Aug ;22(6):339-50.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: