Department of Clinical Oncology, Weston Park Hospital, Whitham Road, Sheffield, S10 2SJ, UK. drpradeephl@yahoo.co.uk.
ABSTRACT: Malignant melanoma can metastasize to virtually any organ of the body. The aggressiveness is determined by the primary site, depth of dermal invasion, presence or absence of ulceration, lymphovascular infiltration and regional lymph node involvement. We report a case of a pregnant woman with a previous history of stage 3 melanoma who presented with cardiac metastasis and placental melanoma infiltration. A review of literature on cardiac and placental involvement of melanoma is also provided.