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Acta Psychiatr Scand. 2007 Jun;115(6):481-6.

Association between antenatal depression and low birthweight in a developing country.

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  • 1Department of Psychological Medicine, University of Manchester, Manchester, UK.

Abstract

OBJECTIVE:

There is a high prevalence of depression in south Asian women. We aimed to examine the association between antenatal depression and low birthweight (LBW) in infants in a rural community in Rawalpindi, Pakistan.

METHOD:

A total of 143 physically healthy mothers with ICD-10 depression in the third trimester of pregnancy and 147 non-depressed mothers of similar gestation were followed from birth. Infant weight was measured and information collected on socioeconomic status, maternal body-mass index and sociodemographic factors.

RESULTS:

Infants of depressed mothers had lower birthweight (mean 2910 g) than infants of non-depressed mothers (mean 3022 g). The relative risk for LBW (< or =2500 g) in infants of depressed mothers was 1.9 (95% CI 1.3-2.9). The association remained significant after adjustment for confounders by multivariate analyses.

CONCLUSION:

Low birthweight is a major public health problem in developing countries. Maternal depression during pregnancy predicts LBW. Interventions aimed at maternal depression may help improve infant outcomes.

PMID:
17498160
[PubMed - indexed for MEDLINE]
PMCID:
PMC1974771
Free PMC Article
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