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1: Bioinformatics. 2007 Jul 15;23(14):1866-7. Epub 2007 May 12.Click here to read Links

DoriC: a database of oriC regions in bacterial genomes.

Gao F, Zhang CT.

Department of Physics, Tianjin University, Tianjin 300072, China.

Replication origins (oriCs) of bacterial genomes currently available in GenBank have been predicted by using a systematic method comprising the Z-curve analysis for nucleotide distribution asymmetry, DnaA box distribution, genes adjacent to candidate oriCs and phylogenetic relationships. These oriCs are organized into a MySQL database, DoriC, which provides extensive information and graphical views of the oriC regions. In addition, users can Blast a query sequence or even a whole genome against DoriC to find a homologous one. DoriC will be updated timely and the latest version is DoriC 1.8, in which oriCs of 425 genomes (468 chromosomes) are identified. AVAILABILITY: DoriC can be accessed from http://tubic.tju.edu.cn/doric/. SUPPLEMENTARY INFORMATION: Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm.

PMID: 17496319 [PubMed - indexed for MEDLINE]