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J Bacteriol. 2007 Jul;189(14):5387-92. Epub 2007 May 11.

QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli.

Author information

  • 1University of Texas Southwestern Medical Center, Department of Microbiology, Dallas, TX 75390-9048, USA.

Abstract

Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded regulator QseA. This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners.

PMID:
17496094
[PubMed - indexed for MEDLINE]
PMCID:
PMC1951852
Free PMC Article

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