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Systems Biology and Bioinformatics Group, Department of Computer Science. University of Rostock, 18051 Rostock, Germany. olaf.wolkenhauer@uni-rostock.de
PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.
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