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Br J Radiol. 2007 Feb;80(950):e44-7.

A giant malignant peripheral nerve sheath tumour of the breast: CT and pathological findings.

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  • 1Department of Radiology, College of Medicine, Korea University, Korea University Guro Hospital, 97 Guro-dong, Guro-ku, Seoul, 152-703, Korea.


Malignant peripheral nerve sheath tumour (MPNST) is a rare soft tissue sarcoma. In particular, primary MPNST of the breast is extremely rare. We report a case of a giant malignant peripheral nerve sheath tumour involving the entire right breast, which was not associated with neurofibromatosis type 1 (NF-1) or previous radiation therapy. A CT scan showed a huge heterogeneous soft tissue mass with well-enhanced nodules at its periphery and low-density internal necrosis, which was confirmed by modified radical mastectomy.

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