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Am J Trop Med Hyg. 2007 May;76(5):915-21.

Risk factors for Trypanosoma cruzi human infection in Barinas State, Venezuela.

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  • 1Facultad de Ciencias de la Salud, Centro Nacional de Referencia de Flebótomos y Otros Vectores, Universidad de Carabobo, Maracay, Venezuela. mdora@movistar.net.ve


This study attempted to quantify the transmission of Trypanosoma cruzi in children less than 15 years of age in Barinas State, Venezuela and investigate risk factors for infection. Among 3,296 children, 4 (0.12%) were seropositive. The mother of one child also was also seropositive, which suggested that congenital transmission is a possible risk factor for Chagas disease in this area. Seroprevalence among the dwellers of 10 localities was 3.3%. Rhodnius prolixus was detected in 7 localities and in 8% of 125 dwellings. A multivariate logistic regression model showed that infection was associated with age, a dirt floor, and distance from houses to palm trees. The risk of infection is increased by the presence of adventitious sylvatic R. prolixus and transient or residual colonies. Insecticide spraying does not seem justified in this scenario, a finding that was also observed in other Latin American countries. New methods are therefore needed for Chagas disease control programs.

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