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    Nat Rev Microbiol. 2007 Jun;5(6):464-70. Epub 2007 May 8.

    Pathogen profiling for disease management and surveillance.

    Source

    Centre for Infectious Diseases and Microbiology Public Health, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Western Clinical School, The University of Sydney, New South Wales, Australia. vitalis@icpmr.wsahs.nsw.gov.au

    Abstract

    The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profiling integrates microbial genomics data into communicable disease control by consolidating phenotypic identity-based methods with DNA microarrays, proteomics, metabolomics and sequence-based typing. Sharing data on pathogen profiles should facilitate our understanding of transmission patterns and the dynamics of epidemics.

    PMID:
    17487146
    [PubMed - indexed for MEDLINE]

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