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Genome Biol. 2007;8(4):210.

Searching genomes for ribozymes and riboswitches.

Author information

  • 1Research Group Molecular Interactions, Department of Genetics, FB 18 Naturwissenschaften, Universit├Ąt Kassel, Kassel, Germany.

Abstract

New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes.

PMID:
17472738
[PubMed - indexed for MEDLINE]
PMCID:
PMC1895996
Free PMC Article

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