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    Proc Natl Acad Sci U S A. 2007 May 15;104(20):8490-5. Epub 2007 Apr 30.

    Neural interactions between flicker-induced self-organized visual hallucinations and physical stimuli.

    Source

    General Dynamics, Inc., Suite 200, 5200 Springfield Pike, Dayton, OH 45431, USA. vince.billock@gd-ais.com

    Abstract

    Spontaneous pattern formation in cortical activity may have consequences for perception, but little is known about interactions between sensory-driven and self-organized cortical activity. To address this deficit, we explored the relationship between ordinary stimulus-controlled pattern perception and the autonomous hallucinatory geometrical pattern formation that occurs for unstructured visual stimulation (e.g., empty-field flicker). We found that flicker-induced hallucinations are biased by the presentation of adjacent geometrical stimuli; geometrical forms that map to cortical area V1 as orthogonal gratings are perceptually opponent in biasing hallucinations. Rotating fan blades and pulsating circular patterns are the most salient biased hallucinations. Apparent motion and fractal (1/f) noise are also effective in driving hallucinatory pattern formation (the latter is consistent with predictions of spatiotemporal pattern formation driven by stochastic resonance). The behavior of these percepts suggests that self-organized hallucinatory pattern formation in human vision is governed by the same cortical properties of localized processing, lateral inhibition, simultaneous contrast, and nonlinear retinotopic mapping that govern ordinary vision.

    PMID:
    17470794
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC1895977
    Free PMC Article

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