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J Am Acad Dermatol. 2007 Jul;57(1):47-53. Epub 2007 Apr 30.

A case-series of 29 patients with lichen planopilaris: the Cleveland Clinic Foundation experience on evaluation, diagnosis, and treatment.

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  • 1Department of Dermatology, The Cleveland Clinic Foundation, OH, USA.

Abstract

BACKGROUND:

Lichen planopilaris results in scaling, atrophy, and permanent alopecia with scarring and is thought to be autoimmune in origin.

OBJECTIVE:

To evaluate the clinical findings of patients with LPP so as to aid in the evaluation and diagnosis of the disease and to review the current effective therapies.

METHODS:

We reviewed the medical records of 29 patients with LPP that were seen in the Department of Dermatology at The Cleveland Clinic Foundation between 1992 and 2003.

RESULTS:

Good responses in the active perimeter were seen with topical steroids, intralesional steroids, and tetracycline and in the inactive end-stage with hair transplants and scalp reductions.

LIMITATIONS:

This study was limited by being retrospective in nature.

CONCLUSION:

Although topical high-potency and intralesional corticosteroids remain the mainstay for treatment of LPP, the use of tetracycline in this disease may be more helpful than once thought.

PMID:
17467854
[PubMed - indexed for MEDLINE]
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