Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada.
While there seems to be general agreement that genetic factors play some role in the etiology of autism, many important questions remain unresolved. The purpose of this paper is to review five issues with respect to the association between low IQ and autism from a familial-genetic viewpoint: (1) does IQ estimate the severity of the autistic genotype?; (2) what is the relationship between probands' and sibs' IQs?; (3) what is the relationship between parents' and probands' IQs?; (4) why do females with autism have lower IQs than males with the disorder?; and (5) does IQ vary with the cause of autism? With respect to each issue, possible resolutions are outlined, as are the implications for understanding the genetic mode of transmission. The review concludes with a possible model for the genetic etiology of autism.
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on