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Ugeskr Laeger. 2007 Apr 2;169(14):1299-302.

[Vitamin D and breast cancer].

[Article in Danish]

Author information

  • 1Arhus Universitetshospital, Arhus Sygehus, Medicinsk-endokrinologisk Afdeling C. rejnmark@post6.tele.dk

Abstract

Active vitamin D increases the differentiation and exerts antiproliferative effects in cancer cells. Recent data suggest that vitamin D is activated locally in cancer cells. Ecologic studies have shown an inverse correlation between breast cancer mortality and sun exposure and dietary vitamin D intake. In clinical studies an impaired vitamin D status is associated with a 20-30% increased breast cancer incidence and 10-20% increased mortality. As vitamin D insufficiency is common, it is important to clarify whether vitamin D status affects the risk and prognosis of breast cancer.

PMID:
17437690
[PubMed - indexed for MEDLINE]
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