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J Invest Dermatol. 2007 May;127(5):991-2.

CaR talk: the calcium receptor finds new places to park.

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  • 1Department of Dermatology, University of California at San Francisco, San Francisco, California 94121, USA.


The study by Tu et al. in this issue details the surprising finding that not only is the CaR active intracellularly but also its intracellular localization includes both the ER, traditionally thought of as the main intracellular Ca2+ signaling store, and the Golgi, more recently shown to be important in keratinocyte signaling.

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