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    Arch Womens Ment Health. 2007;10(3):125-7. Epub 2007 Apr 16.

    Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series.

    Ravindran LN, Woods SA, Steiner M, Ravindran AV.

    Source

    Department of Psychiatry, University of Toronto, Toronto, Canada. arun_ravindran@camh.net

    Abstract

    The efficacy and tolerability of symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD) was evaluated in an open trial. Eight outpatients, aged 18-45 years and diagnosed with PMDD, were treated with 10-20 mg of citalopram from the start of premenstrual symptoms until the onset of menses. Primary efficacy variables were the premenstrual tension scale (PMTS-O) and the clinical global impression of improvement (CGI). Treatment was associated with significant improvement in PMDD symptoms (p < 0.001).

    PMID:
    17431739
    [PubMed - indexed for MEDLINE]

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