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Retrovirology. 2007 Apr 12;4:26.

The silent defense: micro-RNA directed defense against HIV-1 replication.

Author information

  • Department of Biochemistry & Molecular Biology, George Washington University, Washington, DC, USA. akumar@gwu.edu

Abstract

MicroRNAs play critical role in regulating gene expression. MicroRNA profile of particular cell type bears the signature of cell type specific gene expression. Given that viral pathogens replicate by evading host defenses, research is now focused on the miRNA-regulated genes that critically regulate HIV-1 propagation in human host cells.

PMID:
17430590
[PubMed - indexed for MEDLINE]
PMCID:
PMC1865552
Free PMC Article

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