Ann N Y Acad Sci. 2007 Feb;1097:171-4.

Role of aerobic fitness and aging on cerebral white matter integrity.

Marks BL, Madden DJ, Bucur B, Provenzale JM, White LE, Cabeza R, Huettel SA.

Source

Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, USA. marks@email.unc.edu

Abstract

Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cognition may be better preserved in older adults who possess higher levels of aerobic fitness. There are only a few studies, however, investigating potential mechanisms for the improvements in aerobic fitness. Our study suggests that greater aerobic fitness may be related to greater WM integrity in select brain regions.

PMID:: 17413020; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Aerobic fitness and obesity: relationship to cerebral white matter integrity in the brain of active and sedentary older adults. [Br J Sports Med. 2011]
Aerobic fitness and obesity: relationship to cerebral white matter integrity in the brain of active and sedentary older adults.
Marks BL, Katz LM, Styner M, Smith JK. Br J Sports Med. 2011 Dec; 45(15):1208-15. Epub 2010 Jun 17.
White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. [Brain. 2007]
White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study.
Kraus MF, Susmaras T, Caughlin BP, Walker CJ, Sweeney JA, Little DM. Brain. 2007 Oct; 130(Pt 10):2508-19. Epub 2007 Sep 14.
Review Age-related changes in prefrontal white matter measured by diffusion tensor imaging. [Ann N Y Acad Sci. 2005]
Review Age-related changes in prefrontal white matter measured by diffusion tensor imaging.
Salat DH, Tuch DS, Hevelone ND, Fischl B, Corkin S, Rosas HD, Dale AM. Ann N Y Acad Sci. 2005 Dec; 1064:37-49.
Diffusion tensor imaging assessment of brain white matter maturation during the first postnatal year. [AJR Am J Roentgenol. 2007]
Diffusion tensor imaging assessment of brain white matter maturation during the first postnatal year.
Provenzale JM, Liang L, DeLong D, White LE. AJR Am J Roentgenol. 2007 Aug; 189(2):476-86.
Review Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. [Cochrane Database Syst Rev. 2008]
Review Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment.
Angevaren M, Aufdemkampe G, Verhaar HJ, Aleman A, Vanhees L. Cochrane Database Syst Rev. 2008 Apr 16; (2):CD005381. Epub 2008 Apr 16.

See reviews... See all...

Cited by 6 PubMed Central articles

Aerobic fitness and response variability in preadolescent children performing a cognitive control task. [Neuropsychology. 2011]
Aerobic fitness and response variability in preadolescent children performing a cognitive control task.
Wu CT, Pontifex MB, Raine LB, Chaddock L, Voss MW, Kramer AF, Hillman CH. Neuropsychology. 2011 May; 25(3):333-41.
Cardiorespiratory fitness and attentional control in the aging brain. [Front Hum Neurosci. 2011]
Cardiorespiratory fitness and attentional control in the aging brain.
Prakash RS, Voss MW, Erickson KI, Lewis JM, Chaddock L, Malkowski E, Alves H, Kim J, Szabo A, White SM, et al. Front Hum Neurosci. 2011 Jan 14; 4:229. Epub 2011 Jan 14.
Ambient experience in restitutive treatment of aphasia. [Front Hum Neurosci. 2010]
Ambient experience in restitutive treatment of aphasia.
McClung JS, Rothi LJ, Nadeau SE. Front Hum Neurosci. 2010 Nov 2; 4:183. Epub 2010 Nov 2.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Role of aerobic fitness and aging on cerebral white matter integrity.
Role of aerobic fitness and aging on cerebral white matter integrity.
Ann N Y Acad Sci. 2007 Feb ;1097:171-4.

PubMed
A single IGF1 allele is a major determinant of small size in dogs.
A single IGF1 allele is a major determinant of small size in dogs.
Science. 2007 Apr 6 ;316(5821):112-5.

PubMed
Schemas and memory consolidation.
Schemas and memory consolidation.
Science. 2007 Apr 6 ;316(5821):76-82.

PubMed
Genes required for mitotic spindle assembly in Drosophila S2 cells.
Genes required for mitotic spindle assembly in Drosophila S2 cells.
Science. 2007 Apr 20 ;316(5823):417-21. Epub 2007 Apr 5 .

PubMed
Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells.
Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells.
Stem Cells. 2007 Jul ;25(7):1618-26. Epub 2007 Apr 5 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Role of aerobic fitness and aging on cerebral white matter integrity.

Source

Abstract

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 6 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information