p53 and Bad: remote strangers become close friends. [Cell Res. 2007]

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1: Cell Res. 2007 Apr;17(4):283-5. Links

p53 and Bad: remote strangers become close friends.

Jiang P, Du W, Wu M.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Anhui 230027, China.

PMID: 17404594 [PubMed - indexed for MEDLINE]

The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis.
Mol Cell Biol. 2006 Dec; 26(23):9071-82. Epub 2006 Sep 25.

[Mol Cell Biol. 2006]
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis.
J Biol Chem. 2008 Jul 18; 283(29):20060-8. Epub 2008 May 22.

[J Biol Chem. 2008]
Induction of apoptosis by p110C requires mitochondrial translocation of the proapoptotic BCL-2 family member BAD.
FEBS Lett. 2006 Feb 6; 580(3):813-21. Epub 2006 Jan 10.

[FEBS Lett. 2006]
Reviewp53 moves to mitochondria: a turn on the path to apoptosis.
Cell Cycle. 2004 Jul; 3(7):836-9. Epub 2004 Jul 4.

[Cell Cycle. 2004]
Reviewp53 and apoptosis: it's not just in the nucleus anymore.
Mol Cell. 2003 Mar; 11(3):552-4.

[Mol Cell. 2003]
» See reviews... | » See all...

Cited by 1 PubMed Central article

Oscillations of the p53-Akt network: implications on cell survival and death.
Wee KB, Surana U, Aguda BD. PLoS One. 2009; 4(2):e4407. Epub 2009 Feb 6.

[PLoS One. 2009]

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