Preparation of the 5/5-spiroketal of the ritterazines

J Org Chem. 2007 Apr 27;72(9):3454-7. doi: 10.1021/jo0626461. Epub 2007 Mar 31.

Abstract

The enantiomerically pure 5/5-spiroketal required for the synthesis of the ritterazines has been prepared with high diastereocontrol by ring closure followed by equilibration.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Chemistry, Organic / methods*
  • Crystallography, X-Ray
  • Furans / chemical synthesis*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Spiro Compounds / chemical synthesis*
  • Spiro Compounds / chemistry

Substances

  • Furans
  • Spiro Compounds
  • spiroketal