Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Anesth Analg. 2007 Apr;104(4):847-9.

A comparison of laser-assisted drug delivery at two output energies for enhancing the delivery of topically applied LMX-4 cream prior to venipuncture.

Author information

  • 1Department of Anesthesiology and Peri-Operative Medicine, Oregon Health and Science University, Doernbecher Children's Hospital, Portland, Oregon 97239, USA. kohj@ohsu.edu

Abstract

BACKGROUND:

Laser-assisted drug delivery (LAD) has the potential for facilitating topical anesthesia with reduced onset time.

METHODS:

In this randomized, double-blind, crossover study we compared the efficacy and adverse event profile of LAD for topical anesthesia before venipuncture using two output energies (2.0 and 3.5 J/cm2).

RESULTS:

Mean Visual Analog Scale pain scores were not statistically different (P = 0.57) between the low-energy (mean = 6.7) and high-energy (mean = 8.1) lasers.

CONCLUSIONS:

LAD at an energy of 2.0 J/cm2 (570 mJ) is as effective, with similar adverse events, as an energy of 3.5 J/cm2 (1000 mJ) in facilitating topical anesthesia.

PMID:
17377092
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk