Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Int J Gynaecol Obstet. 2007 May;97(2):115-9. Epub 2007 Mar 21.

Maternal serum corticotropin-releasing hormone and ACTH levels as predictive markers of premature labor.

Author information

  • 1Laboratory of Human Reproduction, Department of Obstetrics & Gynecology, Medical School, University of Crete, Heraklion, Greece. makrigia@med.uoc.gr



To investigate whether corticotropin-releasing hormone (CRH) and corticotropin (ACTH) plasma concentrations in women diagnosed with preterm labor are of potential clinical value in the assessment of the risk of preterm birth.


Plasma samples of 79 women diagnosed with preterm labor were used in this study. Samples were divided into three groups based on the week of gestation (24th-28th, 29th-32nd, 33rd-37th). CRH and ACTH values were determined by ELISA.


Mean maternal peripheral plasma values of CRH and ACTH were significantly higher (p<0.001) in women who were initially diagnosed with preterm labor and finally delivered a preterm birth, compared to women with the same diagnosis but with term birth.


CRH and ACTH serum levels in women diagnosed with preterm labor could be used as predictors for the timing of parturition.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk