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Consult Pharm. 2007 Jan;22(1):38-44.

Use of statins and gemfibrozil in patients with type 2 diabetes mellitus and cardiovascular risk factors attending adult day health care centers: an opportunity for pharmacists.

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  • 1International Drug Information Center, Long Island University, Brooklyn, New York 11201, USA. J666666@attglobal.Net

Abstract

OBJECTIVE:

Identify the extent of statin use for primary prevention of macrovascular complications, the extent of statin or gemfibrozil use for the secondary prevention of cardiovascular morbidity and mortality, and the statin doses used in patients with type 2 diabetes and other cardiovascular risk factors.

DESIGN:

Retrospective chart review.

SETTING:

Three adult day health care centers in Brooklyn and Queens, New York.

PATIENTS:

Patients with a diagnosis of type 2 diabetes and either a history of coronary artery disease or at least one other significant cardiovascular risk factor as defined by the American College of Physicians guidelines (i.e., age greater than 55 years, hypertension, left-ventricular hypertrophy, previous cerebrovascular disease, or peripheral arterial disease).

MAIN OUTCOME MEASURES:

Percentage of patients prescribed a statin for primary prevention of macrovascular complications of type 2 diabetes, percentage of patients prescribed a statin or gemfibrozil for secondary prevention of cardiovascular mortality and morbidity, and the percentage of patients on at least moderate doses of statins.

RESULTS:

Ninety-three patients were evaluated-51 in the primary-prevention group and 42 in the secondary-prevention group. In the primary-prevention group, 33 (64.7%) patients were prescribed a statin, while in the secondary-prevention group, 26 (61.9%) patients were on statins, a nonsignificant difference (P = 0.8308). No patients were prescribed gemfibrozil. Of all patients prescribed statins, 63.2% were at least on moderate doses.

CONCLUSION:

This study demonstrates suboptimal treatment with statins in patients with type 2 diabetes and cardiovascular risk factors.

PMID:
17367251
[PubMed - indexed for MEDLINE]
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